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BRL 37344 sodium
CAS No. 127299-93-8
BRL 37344 sodium ( BRL37344 sodium )
产品货号. M11141 CAS No. 127299-93-8
BRL 37344 is a potent and selective β3 adrenoceptor agonist with Ki of 287 nM; has weaker binding affinity for β1 and β2 receptors with Ki of 1750 and 1120 nM, respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥6164 | 有现货 |
|
| 100MG | ￥9315 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称BRL 37344 sodium
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述BRL 37344 is a potent and selective β3 adrenoceptor agonist with Ki of 287 nM; has weaker binding affinity for β1 and β2 receptors with Ki of 1750 and 1120 nM, respectively.
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产品描述BRL 37344 is a potent and selective β3 adrenoceptor agonist with Ki of 287 nM; has weaker binding affinity for β1 and β2 receptors with Ki of 1750 and 1120 nM, respectively; A potent agonist in brown adipocytes (EC50 = 3.3 +/- 0.8 nM) than in white adipocytes (EC50=5.7 nM) or colon (EC50=27.5 nM); Stimulates fuel oxidation by soleus muscle in vitro.Diabetes Discontinued
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同义词BRL37344 sodium
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通路Angiogenesis
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靶点Adrenergic Receptor
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受体Adrenergic Receptor
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研究领域Metabolic Disease
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适应症Diabetes
化学信息
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CAS Number127299-93-8
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分子量385.82
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分子式C19H21NO4ClNa
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纯度>98% (HPLC)
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溶解度——
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SMILESCC(CC1=CC=C(C=C1)OCC(=O)[O-])NCC(C2=CC(=CC=C2)Cl)O.[Na+]
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化学全称Rel-2-[4-[(2S)-2-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]-acetic acid, monosodium salt
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Arch JR, et al. Nature. 1984 May 10-16;309(5964):163-5.
2. Oriowo MA, et al. J Pharmacol Exp Ther. 1996 Apr;277(1):22-7.
3. Board M, et al. Eur J Pharmacol. 2000 Oct 6;406(1):33-40.
2. Oriowo MA, et al. J Pharmacol Exp Ther. 1996 Apr;277(1):22-7.
3. Board M, et al. Eur J Pharmacol. 2000 Oct 6;406(1):33-40.
产品手册
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